该疫苗上周被FDA批准用于紧急用途,并于周一开始在美国各地分发。

通过米勒华忻办公
2020年12月14日
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经过数月的等待,辉瑞的COVID-19疫苗最终是给全国人民的吗卫生保健工作者以及长期护理机构的居民。

虽然第一组以外的人几周甚至几个月都不会接种疫苗,但仍然可以理解每个有资格接种疫苗的人对它有疑问——特别是围绕组成注射的成分。自从辉瑞的疫苗被正式批准美国食品和药物管理局为了在12月11日紧急使用疫苗,公众可以在网上查看疫苗成分。以下是你需要知道的。

首先,关于辉瑞新冠疫苗的工作原理

辉瑞公司的新冠疫苗是使用信使RNA (mRNA)新技术制造的。预计美国食品药品监督管理局(FDA)也将很快批准紧急使用的Moderna新冠疫苗也使用了mRNA技术。

信使rna疫苗的工作原理是编码在导致COVID-19的SARS-CoV-2病毒表面发现的刺突蛋白的一部分疾病控制和预防中心(CDC)。这些mRNA疫苗利用编码的蛋白质片段在你的身体中产生免疫反应,然后产生抗体。(如果你不熟悉它们,抗体是由你的免疫系统产生的蛋白质,用来对抗病毒等感染。它们还可以帮助预防这些感染导致的未来疾病。)

在疫苗引发免疫反应后,你的身体将消除蛋白质和mRNA。然而,抗体会留在原地——只是目前还不知道它们会持续多久。

辉瑞公司的新冠疫苗中含有什么成分?

辉瑞新冠疫苗收到FDA的EUA后,其成分清单在a简报给疫苗接受者和照顾者这是FDA给出的全部成分清单:

  • 信使核糖核酸
  • 脂类(包括((4-羟基丁基)氮杂二基)双(己烷-6,1-二基)双(2-己基癸酸酯),2[(聚乙二醇)-2000]- n, n-双十烷基乙酰胺,1,2-二硬脂酰-sn-甘油-3-磷酸胆碱和胆固醇)
  • 氯化钾
  • 单碱的磷酸钾
  • 氯化钠
  • 磷酸二钠脱水
  • 蔗糖

信使rna我们已经讲过了,但脂质也是一个关键元素。“脂类,也就是脂肪,是非常重要的,因为它们在mRNA周围形成了一个小的球形外壳,”William Schaffner医学博士说传染性疾病范德比尔特大学医学院的专家和教授告诉我们健康

约翰斯·霍普金斯健康安全中心高级学者、传染病专家Amesh A. Adalja医学博士说,脂类是“疫苗传递到你的身体和细胞的方式”健康

脂类“帮助保持信使rna的完整和稳定,直到它进入你的身体并开始工作,”沙夫纳博士说。在那之后,它们会溶解并被你的身体带走。密歇根州立大学药理学和毒理学助理教授杰米·艾伦(Jamie Alan)博士说,正因为如此,脂类对这种疫苗来说是“独一无二的”健康.但是,她说,“其他成分在疫苗中很常见。”

Alan说,氯化钾、磷酸二氢钾、氯化钠和脱水的二碱磷酸钠被用来维持疫苗的pH值和稳定性。(阿达尔贾指出,氯化钠就是盐。)艾伦说,蔗糖是糖的一种形式,“通常被用作稳定剂”。

总的来说,专家说疫苗成分是有意义的。沙夫纳博士说:“这份成分清单上没有什么令人震惊的东西。”这进一步证明,辉瑞的COVID-19疫苗——以及任何将被FDA批准用于紧急情况或公共用途的其他COVID-19疫苗——都是安全的。

截至发稿时,这篇报道中的信息是准确的。然而,随着围绕COVID-19的形势继续发展,一些数据可能自发布以来发生了变化。在《健康》杂志努力使我们的故事尽可能最新的同时,我们也鼓励读者通过使用疾病预防控制中心以及当地的公共卫生部门作为资源。

要想让我们的头条新闻进入你的收件箱,请注册健康生活通讯

The virus that causes COVID-19 is called SARS-CoV-2, short for severe acute respiratory syndrome coronavirus 2. It is a type of coronavirus similar to the one that causes SARS, or severe acute respiratory syndrome.

" }, { "answer_choices": [ { "answer_title": "Fever or chills", "correct_answer": false, "answer_id": "A1", "answer_value": 0, "$vf_selected_count": { "value": 1737, "lastModified": "2021-08-05T02:20:43.000Z" } }, { "answer_title": "Fever dreams", "correct_answer": true, "answer_id": "A2", "answer_value": 1, "$vf_selected_count": { "value": 88455, "lastModified": "2021-08-05T03:59:46.000Z" } }, { "answer_title": "Diarrhea or loose stools", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 16634, "lastModified": "2021-08-05T03:10:58.000Z" } }, { "answer_title": "Breathing difficulties or shortness of breath", "correct_answer": false, "answer_id": "A4", "answer_value": 0, "$vf_selected_count": { "value": 2306, "lastModified": "2021-08-04T22:10:15.000Z" } } ], "answer_type": "text", "question_title": "This is not a possible symptom of COVID-19:", "question_id": "Q2", "answer_description": "

You might have wild dreams when you're ill—fever can do that. But bizarre or emotionally intense fever dreams are not recognized as a symptom of COVID-19.

" }, { "answer_choices": [ { "answer_title": "Wear a mask", "correct_answer": false, "answer_id": "A1", "answer_value": 0, "$vf_selected_count": { "value": 6886, "lastModified": "2021-08-04T22:10:15.000Z" } }, { "answer_title": "Wash your hands", "correct_answer": false, "answer_id": "A2", "answer_value": 0, "$vf_selected_count": { "value": 42251, "lastModified": "2021-08-04T20:27:47.000Z" } }, { "answer_title": "Maintain social distance from others", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 6283, "lastModified": "2021-08-05T01:57:50.000Z" } }, { "answer_title": "Wipe down groceries packaged in cardboard or plastic wrap with bleach", "correct_answer": true, "answer_id": "A4", "answer_value": 1, "$vf_selected_count": { "value": 53713, "lastModified": "2021-08-05T03:59:46.000Z" } } ], "answer_type": "text", "question_title": "To slow the spread of COVID-19, don't do this:", "question_id": "Q3", "answer_description": "

CDC specifically warns against using disinfecting products on food or food packaging. You don't want to accidentally taint your food. Plus, the risk of COVID-19 from handling or consuming food is thought to be low. Use disinfectants like bleach to wipe down tables, countertops, and faucets

" }, { "answer_choices": [ { "answer_title": "A multi-layer medical procedure mask (aka a surgical mask or disposable face mask)", "correct_answer": false, "answer_id": "A1", "answer_value": 0, "$vf_selected_count": { "value": 8746, "lastModified": "2021-08-05T03:53:36.000Z" } }, { "answer_title": "A mask with a vent or valve", "correct_answer": true, "answer_id": "A2", "answer_value": 1, "$vf_selected_count": { "value": 78299, "lastModified": "2021-08-05T03:59:46.000Z" } }, { "answer_title": "A cloth mask made of two or more breathable, washable layers", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 17048, "lastModified": "2021-08-05T03:38:31.000Z" } }, { "answer_title": "A cloth mask over a surgical mask", "correct_answer": false, "answer_id": "A4", "answer_value": 0, "$vf_selected_count": { "value": 5039, "lastModified": "2021-08-05T03:07:17.000Z" } } ], "answer_type": "text", "question_title": "Which masking option is least effective for stopping the spread of COVID-19?", "question_id": "Q4", "answer_description": "

If your mask has a vent or valve, respiratory particles may escape and reach other people. Opt instead for a well-fitting mask with multiple layers, or wear a cloth mask over a disposable mask to secure the underlying mask to your face.

" }, { "answer_choices": [ { "answer_title": "Anal swab testing", "correct_answer": true, "answer_id": "A1", "answer_value": 1, "$vf_selected_count": { "value": 92891, "lastModified": "2021-08-05T03:59:46.000Z" } }, { "answer_title": "Nasal swab testing", "correct_answer": false, "answer_id": "A2", "answer_value": 0, "$vf_selected_count": { "value": 11221, "lastModified": "2021-08-04T23:27:27.000Z" } }, { "answer_title": "Saliva testing", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 2997, "lastModified": "2021-08-04T23:59:39.000Z" } }, { "answer_title": "Throat swab testing", "correct_answer": false, "answer_id": "A4", "answer_value": 0, "$vf_selected_count": { "value": 2023, "lastModified": "2021-08-04T20:56:17.000Z" } } ], "answer_type": "text", "question_title": "Which COVID-19 screening method is not routinely in use in the US?", "question_id": "Q5", "answer_description": "

Most diagnostic tests rely on mucus collected from your nose or throat, and some use saliva that you spit into a test tube. While China is using anal swab testing, that method hasn't caught on in the US.

" }, { "answer_choices": [ { "answer_title": "2 to 12 hours", "correct_answer": false, "answer_id": "A1", "answer_value": 0, "$vf_selected_count": { "value": 4895, "lastModified": "2021-08-05T01:48:01.000Z" } }, { "answer_title": "3 days", "correct_answer": false, "answer_id": "A2", "answer_value": 0, "$vf_selected_count": { "value": 23260, "lastModified": "2021-08-05T03:59:46.000Z" } }, { "answer_title": "14 days", "correct_answer": true, "answer_id": "A3", "answer_value": 1, "$vf_selected_count": { "value": 80188, "lastModified": "2021-08-05T03:53:36.000Z" } }, { "answer_title": "30 days", "correct_answer": false, "answer_id": "A4", "answer_value": 0, "$vf_selected_count": { "value": 790, "lastModified": "2021-08-05T03:17:51.000Z" } } ], "answer_type": "text", "question_title": "How long is the incubation period—the amount time from when you are infected with the novel coronavirus to when you exhibit symptoms?", "question_id": "Q6", "answer_description": "

The incubation is thought to be 14 days, with a median of 4 to 5 days. (But keep in mind that some people never develop symptoms).

" }, { "answer_choices": [ { "answer_title": "A variant", "correct_answer": true, "answer_id": "A1", "answer_value": 1, "$vf_selected_count": { "value": 70967, "lastModified": "2021-08-05T03:59:46.000Z" } }, { "answer_title": "A high viral load", "correct_answer": false, "answer_id": "A2", "answer_value": 0, "$vf_selected_count": { "value": 9434, "lastModified": "2021-08-05T02:57:05.000Z" } }, { "answer_title": "A vaccine", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 11308, "lastModified": "2021-08-05T02:58:47.000Z" } }, { "answer_title": "Another virus, like influenza", "correct_answer": false, "answer_id": "A4", "answer_value": 0, "$vf_selected_count": { "value": 17424, "lastModified": "2021-08-05T03:06:50.000Z" } } ], "answer_type": "text", "question_title": "A mutated version of the virus that causes COVID-19 is called:", "question_id": "Q7", "answer_description": "

Variants of the virus that causes COVID-19 have been identified in the US and around the world. Scientists are studying these variants to learn how they spread and whether current vaccines will protect against them.

" }, { "answer_choices": [ { "answer_title": "Researchers have coined the term \"coronaphobia\" to describe the fear of contracting COVID-19", "correct_answer": false, "answer_id": "A1", "answer_value": 0, "$vf_selected_count": { "value": 8520, "lastModified": "2021-08-05T03:38:31.000Z" } }, { "answer_title": "The virus that causes COVID-19 can sometimes spread through tiny airborne particles", "correct_answer": false, "answer_id": "A2", "answer_value": 0, "$vf_selected_count": { "value": 14326, "lastModified": "2021-08-04T23:05:16.000Z" } }, { "answer_title": "The term \"long-haulers\" refers to people who experience long-term coronavirus symptoms", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 5735, "lastModified": "2021-08-05T03:06:50.000Z" } }, { "answer_title": "COVID-19 is just like having the seasonal flu", "correct_answer": true, "answer_id": "A4", "answer_value": 1, "$vf_selected_count": { "value": 80553, "lastModified": "2021-08-05T03:59:46.000Z" } } ], "answer_type": "text", "question_title": "Which of the following statements is false?", "question_id": "Q8", "answer_description": "

Early on, some people speculated that the novel coronavirus would behave like the seasonal flu. Now we know COVID-19 is much more contagious and spreads more rapidly than influenza.

" }, { "answer_choices": [ { "answer_title": "Women who want to become pregnant some day", "correct_answer": false, "answer_id": "A1", "answer_value": 0, "$vf_selected_count": { "value": 10854, "lastModified": "2021-08-05T03:07:17.000Z" } }, { "answer_title": "Anyone who has had a severe allergic reaction (anaphylaxis) to any vaccine ingredient", "correct_answer": true, "answer_id": "A2", "answer_value": 1, "$vf_selected_count": { "value": 57504, "lastModified": "2021-08-05T03:59:46.000Z" } }, { "answer_title": "People who have recovered from COVID-19", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 9646, "lastModified": "2021-08-04T21:57:03.000Z" } }, { "answer_title": "People with underlying medical conditions", "correct_answer": false, "answer_id": "A4", "answer_value": 0, "$vf_selected_count": { "value": 31129, "lastModified": "2021-08-05T03:17:51.000Z" } } ], "answer_type": "text", "question_title": "Who should not get a COVID-19 vaccine?", "question_id": "Q9", "answer_description": "

CDC does not recommend COVID vaccination if you've had a severe allergic reaction to any COVID vaccine ingredient. Contact your doctor if you have questions about whether it's safe for you to be vaccinated.

" }, { "answer_choices": [ { "answer_title": "You can't get COVID-19 from a COVID-19 shot", "correct_answer": false, "answer_id": "A1", "answer_value": 0, "$vf_selected_count": { "value": 16634, "lastModified": "2021-08-05T03:32:49.000Z" } }, { "answer_title": "Side effects are generally mild and short-lived", "correct_answer": false, "answer_id": "A2", "answer_value": 0, "$vf_selected_count": { "value": 6618, "lastModified": "2021-08-05T03:59:46.000Z" } }, { "answer_title": "It can take a few weeks after getting vaccinated for your body to build immunity to the virus", "correct_answer": false, "answer_id": "A3", "answer_value": 0, "$vf_selected_count": { "value": 3995, "lastModified": "2021-08-04T21:15:44.000Z" } }, { "answer_title": "None of the above", "correct_answer": true, "answer_id": "A4", "answer_value": 1, "$vf_selected_count": { "value": 81886, "lastModified": "2021-08-05T03:53:36.000Z" } } ], "answer_type": "text", "question_title": "Which of the following statements about COVID-19 are false?", "question_id": "Q10", "answer_description": "

Vaccination is safe, effective, and an important tool for beating the pandemic.

" } ], "description": "

News about the novel coronavirus is breaking nearly 24-7, which makes it challenging at best to keep up with the latest scientific evidence, especially when you're bombarded by false or misleading claims on social media. So how much do you really know about COVID-19? Take our quiz to gauge how knowledgeable you are.

", "gate": "none", "intro_page": true, "uuid": "c5d20a0c-6b54-4691-ac5b-7362b5c9e58c", "brand": "health", "headline": "Quiz: How Much Do You Know About Coronavirus?", "results": [ { "result_starting_range": 0, "button": { "_type": "button", "title": "Start Learning More", "src": "https://x.specialoffers.meredith.com/ats/show.aspx?cr=588&fm=201®source=20571" }, "result_ending_range": 3, "result_description": "

Time to bone up on the basic facts about COVID-19. Check out our COVID-19 condition center and subscribe to our daily Healthy Living newsletter and never miss an update.

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While Health is trying to keep our content as up-to-date as possible, we also encourage readers to stay informed on news and recommendations for their own communities by using the CDCWHO, and their local public health department as resources.

", "result_title": "Not Much." }, { "result_starting_range": 4, "button": { "_type": "button", "title": "Learn Some More", "src": "https://x.specialoffers.meredith.com/ats/show.aspx?cr=588&fm=201®source=20571" }, "result_ending_range": 6, "result_description": "

Not bad, but there’s much more to know about this illness. Subscribe to our daily Healthy Living newsletter and never miss an update.

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Is the Coronavirus Worse Than the Flu? Here’s How the Two Illnesses Compare

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While Health is trying to keep our content as up-to-date as possible, we also encourage readers to stay informed on news and recommendations for their own communities by using the CDCWHO, and their local public health department as resources.

", "result_title": "You Know Some Things About Some Things." }, { "result_starting_range": 7, "button": { "_type": "button", "title": "Stay Updated with Newsletters", "src": "https://x.specialoffers.meredith.com/ats/show.aspx?cr=588&fm=201®source=20571" }, "result_ending_range": 8, "result_description": "

Terrific. Keep reading about COIVD-19 on Health.com and stay safe!

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While Health is trying to keep our content as up-to-date as possible, we also encourage readers to stay informed on news and recommendations for their own communities by using the CDCWHO, and their local public health department as resources.

", "result_title": "You Are Certified to Debate on Social Media." }, { "result_starting_range": 9, "button": { "_type": "button", "title": "Sign Up for Newsletters", "src": "https://x.specialoffers.meredith.com/ats/show.aspx?cr=588&fm=201®source=20571" }, "result_ending_range": 10, "result_description": "

You are definitely in the know! Keep coming back to Health.com for the latest information.

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While Health is trying to keep our content as up-to-date as possible, we also encourage readers to stay informed on news and recommendations for their own communities by using the CDCWHO, and their local public health department as resources.

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